CCI-006
CCI-006 is a selective small molecule that acts as a chemosensitizer in MLL-rearranged leukemia. It induces irreversible mitochondrial depolarization by disrupting respiration, which subsequently triggers a pro-apoptotic unfolded protein response. This mechanism supports its investigation in both in vitro and in vivo models of acute leukemia.
Product Specifications
CAS Number
292053-42-0
Product Name Alternative
CCI 006, CCI006, CCI-006, Inhibitor, inhibit, Mitochondrial Metabolism, MitochondrialMetabolism, Mitochondria
Field of Research
Metabolism Research
Purity
96.04% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:8 mg/mL (24.07 mM) ; DMSO:83.33 mg/mL (250.74 mM)
Smiles
COC (=O) C (=C\c1ccc (o1) -c1ccc (cc1) S (N) (=O) =O) \C#N
Molecular Formula
C15H12N2O5S
Molecular Weight
332.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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