CD80-IN-3
CD80-IN-3 is a high-affinity small molecule inhibitor that potently disrupts the CD80/CD28 costimulatory interaction, with a Kd of 125 nM and an EC50 of 630 nM. This compound is a valuable research tool for investigating T-cell activation and immune checkpoint pathways in both cellular assays and preclinical models.
Product Specifications
CAS Number
486449-65-4
Product Name Alternative
Rheumatoid, cell, CD28, CD80IN3, CD-80-IN-3, CD80-IN-3, CD80 IN 3, CD80, autoimmune, arthritis, BB1, BombesinReceptor, Bombesin Receptor, inhibit, inflammatory, Inhibitor
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
96.68% (May vary between batches)
Solubility
DMSO:30 mg/mL (92.8 mM)
Smiles
OC (=O) c1ccc (cc1) -n1nc2c (c[nH]c3c (F) cccc23) c1=O
Molecular Formula
C17H10FN3O3
Molecular Weight
323.28
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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