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SEL120-34A HCl

SEL120-34A HCl is a potent, ATP-competitive, and orally bioavailable small molecule inhibitor of CDK8 and CDK19. It demonstrates antitumor activity in research models and is a valuable tool for investigating the role of the Mediator kinase module in oncology, inflammation, and super-enhancer driven transcription both in vitro and in vivo.

Product Specifications

CAS Number

1609452-30-3

Product Name Alternative

CDK9/cycT, CDK8/CycC, CDK19/CycC, CDK, Cyclin dependent kinase, inhibit, Inhibitor, SEL12034A HCl, SEL-120-34A HCl, SEL120-34A HCl, SEL120 34A HCl

Field of Research

Cell Biology

Purity

98.13% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween-80+45% Saline:0.5 mg/mL (1.11 mM) ; DMSO:8.33 mg/mL (18.49 mM)

Smiles

Cl.Cc1c (Br) c (Br) c2CCCn3c (nc1c23) N1CCNCC1

Molecular Formula

C15H19Br2ClN4

Molecular Weight

450.6

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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