CEP-28122 mesylate salt (1022958-60-6 free base)
CEP-28122 mesylate salt, derived from the free base (CAS 1022958-60-6), is a potent and orally bioavailable inhibitor of ALK with high selectivity, demonstrating an IC50 of 1.9 nM in enzymatic assays. This compound is a valuable research tool for investigating ALK-driven pathologies, such as non-small cell lung cancer, in both cellular and animal models.
Product Specifications
Product Name Alternative
ALK, 1022958-60-6, 1022958-60-6 free base, CEP 28122 mesylate salt (1022958 60 6 free base), CEP 28122 Mesylate, CEP28122 Mesylate, CEP-28122 Mesylate, CEP-28122 mesylate salt, CEP28122 mesylate salt (1022958606 free base)
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.19% (May vary between batches)
Solubility
DMSO:6.4 mg/mL (10.08 mM)
Smiles
COC1=C (C=CC2=C1CC[C@H] (CC2) N3CCOCC3) NC4=NC=C (C (N[C@@H]5[C@@H]6C[C@H] ([C@@H]5C (N) =O) C=C6) =N4) Cl.CS (=O) (O) =O
Molecular Formula
C29H39ClN6O6S
Molecular Weight
635.17
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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