Dexamethasone
Dexamethasone is a potent synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties, acting as a glucocorticoid receptor agonist. It is widely used in research to model conditions like depression and muscle atrophy in vivo, and to study cytokine modulation and autophagy in cellular experiments. Its mechanisms include inhibiting inflammatory exosome release and suppressing LPS-induced macrophage activation.
Product Specifications
CAS Number
50-02-2
Product Name Alternative
Field of Research
Cell Biology, Immunology & Inflammation, Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
Apoptosis inducing glucocorticoid
Form
Powder
Solubility
Soluble in DMSO (up to 40 mg/ml) .
Smiles
F[C@@]12[C@] ([C@]3 ([C@] (C) (C[C@@H]1O) [C@] (C (CO) =O) (O) [C@H] (C) C3) [H]) (CCC=4[C@]2 (C) C=CC (=O) C4) [H]
Molecular Formula
C22H29FO5
Molecular Weight
392.5
Storage Conditions
RT
Notes
For research use only.
Other Product Names
(11β,16α) -9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
Available Sizes
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