Ceranib-2
Ceranib-2 is a cell-permeable ceramidase inhibitor (IC50 = 28 μM in SKOV3 cells) that reduces sphingosine and S1P levels. This activity induces apoptosis and demonstrates anticancer effects in vitro, supporting its use in oncology research focused on sphingolipid metabolism.
Product Specifications
CAS Number
1402830-75-4
Product Name Alternative
S1P, S1P Receptor, S1PReceptor, 3-[ (E) -3- (4-hydroxyphenyl) prop-2-enoyl]-4-phenyl-1H-quinolin-2-one, Apoptosis, Ceramidase, Ceranib-2
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
97.49% (May vary between batches)
Solubility
DMSO:60 mg/mL (157.31 mM) ;10% DMSO+90% Corn Oil:2.5 mg/mL (6.55 mM)
Smiles
COc1ccc (\C=C\C (=O) c2c (-c3ccccc3) c3ccccc3[nH]c2=O) cc1
Molecular Formula
C25H19NO3
Molecular Weight
381.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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