CK-666
CK-666 is a cell-permeable small molecule that potently inhibits the Arp2/3 complex by stabilizing its inactive state, preventing the conformational change required for actin nucleation. This inhibitor is widely used in cell biology research to study actin cytoskeleton dynamics in processes such as cell motility, endocytosis, and pathogen invasion in both in vitro and in vivo models.
Product Specifications
CAS Number
442633-00-3
Product Name Alternative
CK666, CK-666, CK 666, allosteric, active, Actin-related protein 2/3 complex, Arp2/3 Complex, Arp2/3 complex, MicrotubuleAssociated, Microtubule Associated, Inhibitor, inhibit, meshwork, effector, HIV Protease, HIV, HIVProtease, Human immunodeficiency virus, state, trabecular
Field of Research
Neuroscience
Purity
>98%
Bioactivity
ARP2/3 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 45 mg/ml) or in Ethanol (up to 30 mg/ml) .
Smiles
Cc1[nH]c2ccccc2c1CCNC (=O) c1ccccc1F
Molecular Formula
C18H17FN2O
Molecular Weight
296.34
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
2-Fluoro-N-[2-methyl-1H-indol-3-yl) ethyl]benzamide
Available Sizes
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