COH34
COH34 is a potent and selective PARG inhibitor (IC50 0.37 nM) that acts by stabilizing PAR chains at DNA damage sites, thereby trapping DNA repair factors. This mechanism makes it a valuable chemical probe for studying DNA repair pathways in both cellular and biochemical assays.
Product Specifications
CAS Number
906439-72-3
Product Name Alternative
PARG, COH 34, COH34, COH-34, 1-[ (E) - (4-methylphenyl) sulfanyliminomethyl]naphthalen-2-ol
Field of Research
Cell Biology
Purity
98.21% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.41 mM) ; DMSO:15 mg/mL (51.13 mM)
Smiles
Cc1ccc (S\N=C\c2c (O) ccc3ccccc23) cc1
Molecular Formula
C18H15NOS
Molecular Weight
293.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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