DFP00173
DFP00173 is a potent and selective small-molecule inhibitor of aquaporin 3 (AQP3), exhibiting IC50 values of approximately 0.1-0.4 μM against both mouse and human isoforms with selectivity over AQP7 and AQP9. This tool compound is used in research to investigate AQP3's role in cell proliferation, migration, and skin hydration in various in vitro and in vivo models.
Product Specifications
CAS Number
672286-03-2
Product Name Alternative
DFP 00173, DFP00173, DFP-00173, AQP, AQP3, inhibit, Inhibitor, isoforms, homologous, glycerol, human, erythrocytes, permeability, selective
Field of Research
Pharmacology & Drug Discovery
Purity
99.15% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.02 mM) ; DMSO:45 mg/mL (135.48 mM)
Smiles
[O-][N+] (=O) c1cc (NC (=O) Nc2c (Cl) cccc2Cl) cs1
Molecular Formula
C11H7Cl2N3O3S
Molecular Weight
332.16
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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