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DHODH-IN-11

DHODH-IN-11 is a leflunomide-based derivative and a weak inhibitor of dihydroorotate dehydrogenase (DHODH), exhibiting a pKa of 5.03. This small molecule is utilized in biochemical research to study DHODH's role in pyrimidine biosynthesis, with applications in investigating related pathways in both cellular and animal models.

Product Specifications

CAS Number

1263303-95-2

Product Name Alternative

Antiinflammatory, DHODH, DHODH IN 11, DHODHIN11, DHODH-IN-11, Dihydroorotate Dehydrogenase, DNASynthesis, DNA Synthesis, DNA/RNA Synthesis, cyano-oximes, Leflunomide, inhibit, Inhibitor, RNASynthesis, RNA Synthesis, Rat

Field of Research

Cell Biology, Metabolism Research, Molecular Biology

Purity

98.14% (May vary between batches)

Solubility

DMSO:25 mg/mL (94.24 mM)

Smiles

O\N=C (/C#N) C (=O) Nc1ccc (cc1) -c1ccccc1

Molecular Formula

C15H11N3O2

Molecular Weight

265.27

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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