DHODH-IN-11
DHODH-IN-11 is a leflunomide-based derivative and a weak inhibitor of dihydroorotate dehydrogenase (DHODH), exhibiting a pKa of 5.03. This small molecule is utilized in biochemical research to study DHODH's role in pyrimidine biosynthesis, with applications in investigating related pathways in both cellular and animal models.
Product Specifications
CAS Number
1263303-95-2
Product Name Alternative
Antiinflammatory, DHODH, DHODH IN 11, DHODHIN11, DHODH-IN-11, Dihydroorotate Dehydrogenase, DNASynthesis, DNA Synthesis, DNA/RNA Synthesis, cyano-oximes, Leflunomide, inhibit, Inhibitor, RNASynthesis, RNA Synthesis, Rat
Field of Research
Cell Biology, Metabolism Research, Molecular Biology
Purity
98.14% (May vary between batches)
Solubility
DMSO:25 mg/mL (94.24 mM)
Smiles
O\N=C (/C#N) C (=O) Nc1ccc (cc1) -c1ccccc1
Molecular Formula
C15H11N3O2
Molecular Weight
265.27
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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