Donitriptan
Donitriptan is a potent and selective agonist for 5-HT1B and 5-HT1D receptors, exhibiting pKi values of 9.4 and 9.3, respectively. This compound is a valuable research tool for studying serotonergic pathways in models of migraine and neurovascular disorders, applicable in both in vitro and in vivo experimental settings.
Product Specifications
CAS Number
170912-52-4
Product Name Alternative
Inhibit, Inhibitor, 5-HT1B, 5-HT1D, 5-HT1D Receptor, 5-HT1B Receptor, 5-HT Receptor, 5HT Receptor, 5-hydroxytryptamine Receptor, 5HTReceptor, Donitriptan, pki, Serotonin Receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.34% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (8.18 mM) ; DMSO:245 mg/mL (607.22 mM)
Smiles
NCCc1c[nH]c2ccc (OCC (=O) N3CCN (CC3) c3ccc (cc3) C#N) cc12
Molecular Formula
C23H25N5O2
Molecular Weight
403.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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