DOV-216,303 Free Base
DOV-216,303 Free Base is a potent triple reuptake inhibitor of serotonin, norepinephrine, and dopamine (IC50s = 14, 20, and 78 nM, respectively) . It has demonstrated antidepressant-like efficacy in validated preclinical behavioral models, supporting its investigation for mood disorder research in both in vitro and in vivo studies.
Product Specifications
CAS Number
66504-40-3
Product Name Alternative
DAT, Dopamine, Dopamine Receptor, dopamine, Dopamine Transporter, DopamineReceptor, DOV-216,303, DOV216,303 Free Base, DOV-216,303 Free Base, DOV216303, DOV-216303, DOV 216,303 Free Base, DOV 216303, norepinephrine, Norepinephrine, serotonin, Serotonin Transporter, SerotoninTransporter, SLC6A3
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
96.70% (May vary between batches)
Solubility
DMSO:125 mg/mL (547.96 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (17.53 mM) ; Ethanol:95 mg/mL (416.45 mM)
Smiles
Clc1ccc (cc1Cl) C12CC1CNC2
Molecular Formula
C11H11Cl2N
Molecular Weight
228.12
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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