DRI-C21045
Dri-c21045 concentration-dependently inhibits NF-κB activation and CD40L-induced B cell proliferation with IC50 values of 17.1 μM and 4.5 μM, respectively. It selectively blocks the CD40-CD40L protein-protein interaction (IC50 = 0.17 μM) and is applied in immunological research, including in vitro and in vivo studies of autoimmune diseases.
Product Specifications
CAS Number
2101765-81-3
Product Name Alternative
DRI C21045, DRI-C 21045, DRIC21045, DRI-C21045, DRI-C-21045, NF-kB, NFkB, NFκB, NF-κB, inhibit, Inhibitor, TNFR, TNF Receptor, Tumor Necrosis Factor Receptor
Field of Research
Cell Biology, Signal Transduction
Purity
97.20% (May vary between batches)
Solubility
DMSO:2 mg/mL (3.44 mM)
Smiles
COC (=O) c1ccc (cc1) C (=O) Nc1ccc (cc1) -c1ccc (cc1) C (=O) Nc1cccc2cccc (c12) S (O) (=O) =O
Molecular Formula
C32H24N2O7S
Molecular Weight
580.61
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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