LHF-535
LHF-535 is a broad-spectrum antiviral compound exhibiting potent activity against several hemorrhagic fever arenaviruses, with EC50 values below 1 μM for Lassa, Machupo, and Junin viruses. It demonstrates activity against VSVg pseudotyped viruses in the 1-10 μM range. This small molecule is a valuable research tool for in vitro antiviral mechanism studies and for probing host-pathogen interactions.
Product Specifications
CAS Number
1450929-77-7
Product Name Alternative
Arenavirus, antiviral, inhibit, LHF 535, LHF535, LHF-535, Inhibitor, VirusProtease, Virus Protease
Field of Research
Immunology & Inflammation, Infectious Disease & Virology
Purity
99.60% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8 mM) ; DMSO:96.67 mg/mL (234.34 mM) ; H2O:< 0.1 mg/mL (insoluble)
Smiles
CC (C) Oc1ccc (cc1) -n1cnc2cc (\C=C/c3ccc (cc3) C (C) (C) O) ccc12
Molecular Formula
C27H28N2O2
Molecular Weight
412.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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