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Elubrixin

Elubrixin (SB-656933) is a potent, selective, and orally active antagonist of CXCR2/IL-8 receptors. It inhibits neutrophil activation, demonstrated by blocking CD11b upregulation and shape change in vitro, and is used in research models of inflammatory bowel disease and airway inflammation.

Product Specifications

CAS Number

688763-64-6

Product Name Alternative

SB 656933, SB656933, SB-656933, inhibit, IL-8, ILReceptor, Inhibitor, neutrophil-mediated, Elubrixin, IL Receptor, Interleukin Related, airway, anti-inflammatory, bowel, CD11b, CXC chemokine receptors, CXCR2, CXCR

Field of Research

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery

Purity

98.65% (May vary between batches)

Solubility

DMSO:10 mg/mL (21.58 mM)

Smiles

S (=O) (=O) (C1=C (O) C (NC (NC2=C (Cl) C (F) =CC=C2) =O) =CC=C1Cl) N3CCNCC3

Molecular Formula

C17H17Cl2FN4O4S

Molecular Weight

463.31

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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