Elubrixin
Elubrixin (SB-656933) is a potent, selective, and orally active antagonist of CXCR2/IL-8 receptors. It inhibits neutrophil activation, demonstrated by blocking CD11b upregulation and shape change in vitro, and is used in research models of inflammatory bowel disease and airway inflammation.
Product Specifications
CAS Number
688763-64-6
Product Name Alternative
SB 656933, SB656933, SB-656933, inhibit, IL-8, ILReceptor, Inhibitor, neutrophil-mediated, Elubrixin, IL Receptor, Interleukin Related, airway, anti-inflammatory, bowel, CD11b, CXC chemokine receptors, CXCR2, CXCR
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
98.65% (May vary between batches)
Solubility
DMSO:10 mg/mL (21.58 mM)
Smiles
S (=O) (=O) (C1=C (O) C (NC (NC2=C (Cl) C (F) =CC=C2) =O) =CC=C1Cl) N3CCNCC3
Molecular Formula
C17H17Cl2FN4O4S
Molecular Weight
463.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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