EMPA
EMPA is a potent, selective, and reversible OX2 orexin receptor antagonist, exhibiting high affinity with KD values of 1.1 nM (human) and 1.4 nM (rat) in membrane binding assays. This compound is a valuable research tool for investigating sleep-wake regulation, narcolepsy, and metabolic disorders in both in vitro and in vivo models.
Product Specifications
CAS Number
680590-49-2
Product Name Alternative
EMPA, Hypocretin Receptor, HCRT Receptor, Inhibitor, inhibit, OX2, OX2 Receptor, OX Receptor, Orexin Receptor (OX Receptor), OXReceptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.11% (May vary between batches)
Solubility
DMSO:230 mg/mL (506.01 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (11 mM)
Smiles
N (S (=O) (=O) C1=C (C) C=CC=C1) (CC (N (CC=2C=CC=NC2) CC) =O) C=3C=CC (OC) =NC3
Molecular Formula
C23H26N4O4S
Molecular Weight
454.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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