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Ent-Ezetimibe

Ezetimibe is a potent cholesterol absorption inhibitor that acts by blocking the Niemann-Pick C1-like1 (NPC1L1) protein and also functions as an Nrf2 activator. Its RRS-enantiomer, ent-Ezetimibe (ent-SCH 58235), is used in research to study sterol transport and oxidative stress pathways in vitro and in vivo.

Product Specifications

CAS Number

1376614-99-1

Product Name Alternative

Drug Metabolite, Inhibitor, inhibit, entEzetimibe, ent-Ezetimibe, ent-SCH 58235, ent-SCH58235, ent-SCH-58235, ent Ezetimibe, RRS-enantiomer

Field of Research

Immunology & Inflammation; Pharmacology & Drug Discovery, Metabolism Research

Purity

98.30% (May vary between batches)

Solubility

DMSO:60 mg/mL (146.55 mM)

Smiles

C (C[C@@H] (O) C1=CC=C (F) C=C1) [C@H]2[C@@H] (N (C2=O) C3=CC=C (F) C=C3) C4=CC=C (O) C=C4

Molecular Formula

C24H21F2NO3

Molecular Weight

409.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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