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Camptothecin

Camptothecin is a natural alkaloid and potent topoisomerase I inhibitor (IC50=679 nM) with established antitumor activity. It is widely used in cancer research to induce apoptosis in both in vitro cell studies and in vivo tumor models.

Product Specifications

CAS Number

7689-03-4

Product Name Alternative

CPT, DNA topoisomerase I, (S) - (+) -Camptothecin, ADC Cytotoxin, alkaloid, ADCCytotoxin, Apoptosis, Antibiotic, Camptothecin, Campathecin, Fungal, HIF-1α, NSC100880, NSC-100880, NSC 100880, InfluenzaVirus, Influenza Virus, microRNAs, MicroRNA, miRN, miRNA, Topoisomerase, Topo I, Top1

Field of Research

Cell Biology

Purity

>98%

Bioactivity

Topoisomerase I inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 5 mg/ml) .

Smiles

C (C) [C@]1 (O) C2=C (C (=O) N3C (=C2) C=4C (C3) =CC=5C (N4) =CC=CC5) COC1=O

Molecular Formula

C20H16N2O4

Molecular Weight

348.4

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

(S) -4-Ethyl-4-hydroxy-1H-pyrano-[3',4':6,7]indolizino[1,2-b]quinoline-3,14 (4H,12H) -dione

Available Sizes

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