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(+) -Shikonin

(+) -Shikonin is a bioactive natural compound that acts as a TMEM16A chloride channel inhibitor and a selective PKM2 inhibitor. It has demonstrated antitumor and anti-inflammatory properties in research studies, supporting its investigation in cancer biology and inflammation models both in vitro and in vivo.

Product Specifications

CAS Number

517-89-5

Product Name Alternative

Chloride channel, Chloride Channel, Chloridechannel, Cl? Channels, Alkanna Red, (+) -Shikonin, (R) - (+) -Shikonin, C.I. 75535, Anchusa acid, NSC252844, NSC-252844, NSC 252844, Inhibitor, Isoarnebin 4, Isoarnebin4, Isoarnebin-4, inhibit, NF-kB, NFkB, Pyruvate Kinase, NF-κB, NFκB, Nuclear factor-kappaB, Nuclear factor-κB, Human immunodeficiency virus, HIV, HIV Protease, HIVProtease, Shikonin, TNF-α, TNFR, PKM2, TMEM16A chloride channel, TNF Receptor, Tumor Necrosis Factor Receptor

Field of Research

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery, Protein Biochemistry, Signal Transduction

Purity

98.13% (May vary between batches)

Solubility

Ethanol:13.00 mg/mL (45.09 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5.70 mg/mL (19.77 mM) ; DMSO:130.00 mg/mL (450.92 mM) ; H2O:Insoluble

Smiles

CC (C) =CC[C@@H] (O) C1=CC (=O) c2c (O) ccc (O) c2C1=O

Molecular Formula

C16H16O5

Molecular Weight

288.30

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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