(+) -Shikonin
(+) -Shikonin is a bioactive natural compound that acts as a TMEM16A chloride channel inhibitor and a selective PKM2 inhibitor. It has demonstrated antitumor and anti-inflammatory properties in research studies, supporting its investigation in cancer biology and inflammation models both in vitro and in vivo.
Product Specifications
CAS Number
517-89-5
Product Name Alternative
Chloride channel, Chloride Channel, Chloridechannel, Cl? Channels, Alkanna Red, (+) -Shikonin, (R) - (+) -Shikonin, C.I. 75535, Anchusa acid, NSC252844, NSC-252844, NSC 252844, Inhibitor, Isoarnebin 4, Isoarnebin4, Isoarnebin-4, inhibit, NF-kB, NFkB, Pyruvate Kinase, NF-κB, NFκB, Nuclear factor-kappaB, Nuclear factor-κB, Human immunodeficiency virus, HIV, HIV Protease, HIVProtease, Shikonin, TNF-α, TNFR, PKM2, TMEM16A chloride channel, TNF Receptor, Tumor Necrosis Factor Receptor
Field of Research
Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery, Protein Biochemistry, Signal Transduction
Purity
98.13% (May vary between batches)
Solubility
Ethanol:13.00 mg/mL (45.09 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5.70 mg/mL (19.77 mM) ; DMSO:130.00 mg/mL (450.92 mM) ; H2O:Insoluble
Smiles
CC (C) =CC[C@@H] (O) C1=CC (=O) c2c (O) ccc (O) c2C1=O
Molecular Formula
C16H16O5
Molecular Weight
288.30
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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