LY3381916
LY3381916 is a potent and selective brain-penetrant small molecule inhibitor of IDO1. It uniquely targets the apo-form of the enzyme prior to heme incorporation. This tool compound is used in both in vitro and in vivo research to investigate immunomodulation and cancer immunotherapy pathways.
Product Specifications
CAS Number
2166616-75-5
Product Name Alternative
Indoleamine2,3Dioxygenase, Indoleamine 2,3-Dioxygenase (IDO), Indoleamine2,3Dioxygenase (IDO), Indoleamine 2,3Dioxygenase (IDO), Indoleamine 2,3-Dioxygenase, inhibit, IDO, IDO1, IDO1 IN 5, IDO1IN5, IDO-1-IN-5, IDO1-IN-5, Inhibitor
Field of Research
Metabolism Research
Purity
96.70% (May vary between batches)
Solubility
DMSO:300 mg/mL (756.72 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (12.61 mM)
Smiles
C[C@@H] (NC (=O) c1ccc (F) cc1) c1ccc2N (CCc2c1) C (=O) C1CCOCC1
Molecular Formula
C23H25FN2O3
Molecular Weight
396.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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