LY2365109 hydrochloride
LY2365109 hydrochloride is a potent, selective inhibitor of the human glycine transporter 1 (hGlyT1a), demonstrating an IC50 of 15.8 nM in cellular uptake assays. This compound is a valuable research tool for investigating GlyT1 function in preclinical models of schizophrenia and cognitive disorders, both in vitro and in vivo.
Product Specifications
CAS Number
1779796-27-8
Product Name Alternative
Seizure, uptake, Inhibitor, hGlyT1, glycine, Glycine transporters, GlyT1, GlyT, Human, LY2365109 Hydrochloride, LY2365109 hydrochloride, LY-2365109 hydrochloride, LY-2365109 Hydrochloride, LY2365109, LY-2365109, LY 2365109, LY 2365109 Hydrochloride, inhibit, neuroblastoma
Field of Research
Neuroscience
Purity
98.27% (May vary between batches)
Solubility
DMSO:30 mg/mL (71.11 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.74 mM)
Smiles
Cl.CN (CCOc1ccc (cc1C (C) (C) C) -c1ccc2OCOc2c1) CC (O) =O
Molecular Formula
C22H28ClNO5
Molecular Weight
421.91
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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