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M‐89

M-89 is a potent and selective small molecule inhibitor of the menin-MLL interaction, exhibiting a 1.4 nM Kd for menin. It is a valuable research tool for investigating MLL-rearranged leukemia mechanisms in both cellular and animal models, supporting the development of targeted therapeutics.

Product Specifications

CAS Number

2363165-42-6

Product Name Alternative

Inhibit, M?89, M‐89, menin, Menin-MLL, HistoneMethyltransferase, Histone Methyltransferase, Inhibitor, Epigenetic Reader Domain, EpigeneticReaderDomain

Field of Research

Epigenetics & Chromatin

Purity

98.38% (May vary between batches)

Solubility

DMSO:7 mg/mL (10.64 mM)

Smiles

CNC (=O) O[C@H]1CCC[C@@H]1[C@@]1 (CN (C) Cc2ccccc12) C1CCN (CC2CN (C2) c2ccc (cc2) S (=O) (=O) c2ccncc2) CC1

Molecular Formula

C37H47N5O4S

Molecular Weight

657.87

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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