M‐89
M-89 is a potent and selective small molecule inhibitor of the menin-MLL interaction, exhibiting a 1.4 nM Kd for menin. It is a valuable research tool for investigating MLL-rearranged leukemia mechanisms in both cellular and animal models, supporting the development of targeted therapeutics.
Product Specifications
CAS Number
2363165-42-6
Product Name Alternative
Inhibit, M?89, M‐89, menin, Menin-MLL, HistoneMethyltransferase, Histone Methyltransferase, Inhibitor, Epigenetic Reader Domain, EpigeneticReaderDomain
Field of Research
Epigenetics & Chromatin
Purity
98.38% (May vary between batches)
Solubility
DMSO:7 mg/mL (10.64 mM)
Smiles
CNC (=O) O[C@H]1CCC[C@@H]1[C@@]1 (CN (C) Cc2ccccc12) C1CCN (CC2CN (C2) c2ccc (cc2) S (=O) (=O) c2ccncc2) CC1
Molecular Formula
C37H47N5O4S
Molecular Weight
657.87
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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