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MELK-8a hydrochloride

MELK-8a hydrochloride is a highly potent small molecule inhibitor of Maternal Embryine Leucine Zipper Kinase (MELK), exhibiting an IC50 of 2 nM. This compound is a valuable research tool for investigating MELK function in cancer biology, stem cell regulation, and tumorigenesis in both cellular and animal models.

Product Specifications

CAS Number

2096992-20-8

Product Name Alternative

Inhibit, NVS-MELK8a, Maternal embryonic leucine zipper kinase, MELK, MELK 8a hydrochloride, MELK-8a, MELK8a hydrochloride, MELK-8a Hydrochloride, Inhibitor

Field of Research

Cell Biology, Signal Transduction

Purity

99.57% (May vary between batches)

Solubility

H2O:100 mg/mL (213.21 mM) ; DMSO:8 mg/mL (17.06 mM)

Smiles

Cl.CN1CCN (CC1) c1ccc (cc1) -n1cc (cn1) -c1ccncc1OCC1CCNCC1

Molecular Formula

C25H33ClN6O

Molecular Weight

469.02

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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