MELK-IN-1
MELK-IN-1 is a highly potent and selective small molecule inhibitor of Maternal Embryine Leucine Zipper Kinase (MELK), exhibiting an IC50 of 3 nM and a Ki of 0.39 nM. This compound is a valuable chemical probe for investigating MELK function in cancer cell proliferation, stem cell biology, and tumor growth in both cellular and animal models.
Product Specifications
CAS Number
2095596-44-2
Product Name Alternative
Inhibit, Nintedanib Impurity L, Inhibitor, MELK, MELKIN1, MELK-IN-1, MELK IN 1, MELK inhibitor 17, Maternal embryonic leucine zipper kinase
Field of Research
Cell Biology, Signal Transduction
Purity
99.14% (May vary between batches)
Solubility
DMSO:Insoluble
Smiles
COC (=O) c1ccc2NC (=O) \C (=C (/Nc3ccc (cc3) N (C) C (=O) CN3CCN (C) CC3) c3ccccc3) c2c1
Molecular Formula
C31H33N5O4
Molecular Weight
539.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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