Mibefradil dihydrochloride
Mibefradil dihydrochloride is a calcium channel blocker exhibiting moderate selectivity for T-type over L-type channels (IC50s of 2.7 μM and 18.6 μM, respectively) . It is a research tool used in cardiovascular and neurological studies, with applications in both in vitro electrophysiology and in vivo models of hypertension and arrhythmia.
Product Specifications
CAS Number
116666-63-8
Product Name Alternative
Ca channels, Ca2+ channels, Calcium Channel, CalciumChannel, Inhibitor, inhibit, Mibefradil, Mibefradil dihydrochloride, Mibefradil Dihydrochloride, L-type calcium channel, T-type calcium channel, Ro 40-5967, Ro 40-5967 (dihydrochloride)
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
98.66% (May vary between batches)
Solubility
H2O:122 mg/mL (214.58 mM)
Smiles
Cl.Cl.COCC (=O) O[C@]1 (CCN (C) CCCc2nc3ccccc3[nH]2) CCc2cc (F) ccc2[C@@H]1C (C) C
Molecular Formula
C29H40Cl2FN3O3
Molecular Weight
568.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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