MK2-IN-3 hydrate
MK2-IN-3 hydrate is a potent, selective, and orally bioavailable ATP-competitive inhibitor of MAPKAP-K2 (MK-2), exhibiting an IC50 of 0.85 nM. This small molecule is a valuable research tool for investigating MK-2 signaling in inflammatory diseases and cancer, with utility in both cellular and animal models of these conditions.
Product Specifications
CAS Number
1186648-22-5
Product Name Alternative
MAP kinase activated protein kinase 2, MAPK activated protein kinase 2, MAPKAP kinase 2, MAPKAPK2 (MK2), ERK2, Mitogen-activated protein kinase activated protein kinase 2, MK5, MK-5, MK-3, MK-2 Inhibitor III, MK2 IN 3 hydrate, MK2IN3 hydrate, MK-2-IN-3 hydrate, MK2-IN-3 Hydrate, MK3, MK2, MK-2, MNK1, inhibit, Inhibitor
Field of Research
Signal Transduction
Purity
99.14% (May vary between batches)
Solubility
DMSO:65 mg/mL (181.37 mM)
Smiles
O=C1C2=C (NC (C3=CC (C4=CC5=CC=CC=C5N=C4) =NC=C3) =C2) CCN1.[H]O[H]
Molecular Formula
C21H18N4O2
Molecular Weight
358.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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