ML-180
ML-180 (SR1848) is a potent small molecule inverse agonist of the orphan nuclear receptor LRH-1 (NR5A2), exhibiting an IC50 of 3.7 μM. This compound is a valuable research tool for studying LRH-1's role in metabolism, inflammation, and cancer in both cellular and animal models.
Product Specifications
CAS Number
863588-32-3
Product Name Alternative
Cancers, factor-1, Inhibitor, homolog, inhibit, NR5A2, NR5A1, liver, nuclear, Orphan, orphan nuclear receptor NR5A2, LRH-1, ML180, ML-180, ML 180, SF-1, receptor, SR1848, SR-1848, SR 1848, steroidogenic
Field of Research
Pharmacology & Drug Discovery
Purity
99.74% (May vary between batches)
Solubility
DMSO:11 mg/mL (28.29 mM)
Smiles
Clc1cccc (c1) N1CCN (CC1) c1cc (=O) n (C2CCCCC2) c (=O) [nH]1
Molecular Formula
C20H25ClN4O2
Molecular Weight
388.89
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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