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ML604440

ML604440 is a cell-permeable small molecule that selectively inhibits the immunoproteasome subunit β1i (LMP2) . This inhibitor is utilized in research to study immunoproteasome function in autoimmune diseases, inflammation, and cancer, both in cellular and animal models.

Product Specifications

CAS Number

1140517-08-3

Product Name Alternative

EAE, cell-permeable, CD4+T cell, autoimmune disease, inhibit, LMP7-deficient mice splenocytes, ML604440, ML-604440, ML 604440, experimental colitis, Inhibitor, human PBMCs, Proteasome

Field of Research

Protein Biochemistry

Purity

95.24% (May vary between batches)

Solubility

DMSO:100 mg/mL (257.61 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.3 mM)

Smiles

C (NC (C (N[C@@H] (CC (C) C) B (O) O) =O) (C) C) (=O) C1=C (C (F) (F) F) C=CC=C1

Molecular Formula

C17H24BF3N2O4

Molecular Weight

388.19

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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