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MRGPRX1 agonist 1

MRGPRX1 agonist 1 is a potent and selective small molecule activator of the Mas-related G-protein-coupled receptor X1, exhibiting an EC50 of 50 nM. This compound is a valuable research tool for investigating MRGPRX1-mediated signaling in vitro and its role in itch, pain, and allergic responses in preclinical models.

Product Specifications

CAS Number

2377379-39-8

Product Name Alternative

Inhibit, MRGPRX1, MRGPRX1 agonist 1, MRGPRX-1 agonist 1, Inhibitor

Field of Research

Pharmacology & Drug Discovery

Purity

99.59% (May vary between batches)

Solubility

DMSO:125 mg/mL (287.03 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.18 mM)

Smiles

COc1ccccc1S (=O) (=O) Nc1ccc (C) cc1Oc1ccc2c (N) nccc2c1

Molecular Formula

C23H21N3O4S

Molecular Weight

435.5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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