Mutant IDH1-IN-2
Mutant IDH1-IN-2 is a potent and selective inhibitor of mutant isocitrate dehydrogenase 1, exhibiting IC50 values below 22 nM in biochemical assays. This small molecule is a valuable research tool for investigating oncogenic IDH1 function in cancers like glioma and AML, supporting both in vitro and in vivo mechanistic studies.
Product Specifications
CAS Number
1429176-69-1
Product Name Alternative
IsocitrateDehydrogenase (IDH), IsocitrateDehydrogenase, Isocitrate Dehydrogenase (IDH), Isocitrate Dehydrogenase, Mutant IDH1IN2, Mutant IDH-1-IN-2, Mutant IDH1-IN-2, Mutant IDH1 IN 2, inhibit, Inhibitor, IDH
Field of Research
Metabolism Research
Purity
99.11% (May vary between batches)
Solubility
DMSO:9 mg/mL (19.59 mM) ;10% DMSO+90% Corn Oil:0.5 mg/mL (1.09 mM) ; H2O:< 0.1 mg/mL (insoluble)
Smiles
CC (C) [C@H]1COC (=O) N1c1ccnc (N[C@@H] (C) c2ccc (CN3CCC (F) (F) CC3) cc2) n1
Molecular Formula
C24H31F2N5O2
Molecular Weight
459.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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