Ned 19
Ned-19 is a selective, membrane-permeant antagonist of NAADP-mediated calcium signaling. It potently suppresses tumor progression in murine models, inhibiting primary tumor growth, angiogenesis, and lung metastasis formation. This compound is a valuable research tool for studying NAADP function in cancer biology and metastasis in both in vitro and in vivo experimental systems.
Product Specifications
CAS Number
874374-25-1
Product Name Alternative
Calcium Channel, Ca2+, CalciumChannel, Ned 19
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
98.55% (May vary between batches)
Solubility
DMSO:60 mg/mL (116.6 mM)
Smiles
C (O) (=O) C1CC2=C (C (N1) C3=CC (CN4CCN (CC4) C5=C (F) C=CC=C5) =C (OC) C=C3) NC=6C2=CC=CC6
Molecular Formula
C30H31FN4O3
Molecular Weight
514.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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