NMDA-IN-1
NMDA-IN-1 is a potent, selective NMDA receptor antagonist with high affinity for the NR2B subunit (Ki = 0.85 nM) . It effectively inhibits NR2B-mediated calcium influx (IC50 = 9.7 nM) . This compound is a valuable research tool for studying NMDA receptor function in neurological disorders, applicable in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
700878-19-9
Product Name Alternative
NMDA IN 1, NMDA, NMDAIN1, NMDA-IN-1, Ionotropic glutamate receptors, inhibit, Inhibitor, iGluR
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
97.01% (May vary between batches)
Solubility
DMSO:12 mg/mL (31.93 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.66 mM)
Smiles
Cl.Cl.Oc1ccc2[nH]c (CN3CCC (Cc4ccccc4F) CC3) nc2c1
Molecular Formula
C20H23ClFN3O
Molecular Weight
375.87
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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