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NMDA-IN-1

NMDA-IN-1 is a potent, selective NMDA receptor antagonist with high affinity for the NR2B subunit (Ki = 0.85 nM) . It effectively inhibits NR2B-mediated calcium influx (IC50 = 9.7 nM) . This compound is a valuable research tool for studying NMDA receptor function in neurological disorders, applicable in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

700878-19-9

Product Name Alternative

NMDA IN 1, NMDA, NMDAIN1, NMDA-IN-1, Ionotropic glutamate receptors, inhibit, Inhibitor, iGluR

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

97.01% (May vary between batches)

Solubility

DMSO:12 mg/mL (31.93 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.66 mM)

Smiles

Cl.Cl.Oc1ccc2[nH]c (CN3CCC (Cc4ccccc4F) CC3) nc2c1

Molecular Formula

C20H23ClFN3O

Molecular Weight

375.87

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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