NMS-P715
NMS-P715 is a potent, ATP-competitive small molecule inhibitor of MPS1 kinase with high selectivity and an IC50 of 182 nM. It is a valuable research tool for studying mitosis, chromosome segregation, and cancer biology in both cellular and in vivo models.
Product Specifications
CAS Number
1202055-32-0
Product Name Alternative
Casein Kinase, CaseinKinase, CK2, Monopolar spindle 1, Mps1, inhibit, NMS-P 715, NMS P715, NMSP715, NMS-P715, NMS-P-715, NEK6, MELK, Inhibitor
Field of Research
Metabolism Research, Neuroscience, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.41% (May vary between batches)
Solubility
DMSO:2 mg/mL (2.96 mM)
Smiles
CCc1cccc (CC) c1NC (=O) c1nn (C) c-2c1CCc1cnc (Nc3ccc (cc3OC (F) (F) F) C (=O) NC3CCN (C) CC3) nc-21
Molecular Formula
C35H39F3N8O3
Molecular Weight
676.73
Storage Conditions
-20°C
Notes
For research use only.
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