Ilginatinib
Ilginatinib (NS-018) is a potent, orally administered small molecule inhibitor targeting JAK2. It is utilized in preclinical research for studying myeloproliferative neoplasms, demonstrating activity in both cellular assays and animal models of disease.
Product Specifications
CAS Number
1239358-86-1
Product Name Alternative
Bioavailable, NS 018, NS018, NS-018, inhibit, Inhibitor, Janus kinase, JAK3, JAK, JAK1, JAK2, orally, Ilginatinib, TyrosineKinases, Tyrosine Kinases, Tyk2
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.40% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.14 mM) ; DMSO:50 mg/mL (128.39 mM)
Smiles
C[C@H] (Nc1cc (cc (Nc2cnccn2) n1) -c1cnn (C) c1) c1ccc (F) cc1
Molecular Formula
C21H20FN7
Molecular Weight
389.43
Storage Conditions
-20°C
Notes
For research use only.
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