Ilginatinib maleate
Ilginatinib maleate (NS-018 maleate) is an orally active and potent small molecule inhibitor targeting JAK2. It is utilized in preclinical research for investigating myeloproliferative neoplasms and has demonstrated activity in both cellular assays and animal models.
Product Specifications
CAS Number
1354799-87-3
Product Name Alternative
TyrosineKinases, Tyrosine Kinases, Tyk2, Inhibitor, NS018, NS-018, NS018 Maleate, NS-018 Maleate, NS-018 maleate, NS 018, NS 018 Maleate, JAK2, JAK1, JAK, Janus kinase, inhibit, JAK3, Ilginatinib, Ilginatinib maleate, Ilginatinib Maleate, orally, bioavailable
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.68% (May vary between batches)
Solubility
DMSO:50 mg/mL (98.91 mM) ; H2O:< 0.1 mg/mL (insoluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.96 mM)
Smiles
OC (=O) \C=C/C (O) =O.C[C@H] (Nc1cc (cc (Nc2cnccn2) n1) -c1cnn (C) c1) c1ccc (F) cc1
Molecular Formula
C25H24FN7O4
Molecular Weight
505.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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