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NTP42

NTP42 is a potent and selective small molecule antagonist of the thromboxane A2 receptor (TP), exhibiting an IC50 of 3.278 nM. It is a valuable research tool for investigating TP receptor signaling in cardiovascular and thrombotic diseases, applicable in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

2055599-51-2

Product Name Alternative

Arterial, hypertension, inhibit, Inhibitor, NTP 42, NTP42, NTP-42, PAH, Prostaglandin Receptor, ProstaglandinReceptor, pulmonary, thromboxane, TXA2R, TXA2

Field of Research

Immunology & Inflammation, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery

Purity

97.55% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.88 mM) ; DMSO:30 mg/mL (58.19 mM)

Smiles

CC (C) (C) NC (=O) NS (=O) (=O) c1cc (ccc1Oc1cccc (c1) -c1ccc (OC (F) F) cc1) C#N

Molecular Formula

C25H23F2N3O5S

Molecular Weight

515.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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