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ON 146040

ON 146040 is a potent small molecule inhibitor targeting PI3Kα and PI3Kδ isoforms with IC50 values of 14 nM and 20 nM, respectively. This compound is a valuable research tool for investigating PI3K signaling in oncology and immunology, supporting both in vitro biochemical assays and in vivo disease model studies.

Product Specifications

CAS Number

1404231-34-0

Product Name Alternative

Abl1, BcrAbl, ON 146040, ON146040, ON-146040, PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ, ZINC211117138, ZINC-211117138, ZINC 211117138

Field of Research

Cardiovascular Research, Signal Transduction

Purity

97.39% (May vary between batches)

Solubility

DMSO:4.9 mg/mL (10.01 mM)

Smiles

CN1CCN (CC1) c1ccc (Nc2ncc3NC (=O) \C (Sc3n2) =C\c2ccc (cc2) [N+] ([O-]) =O) cc1

Molecular Formula

C24H23N7O3S

Molecular Weight

489.55

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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