P-gp inhibitor 1
P-gp inhibitor 1 is a potent small molecule that reverses P-glycoprotein-mediated multidrug resistance, demonstrating an EC50 of 57.9 nM in K562/A02 cell assays. This compound is a valuable research tool for studying drug efflux mechanisms and overcoming chemoresistance in both in vitro and in vivo cancer models.
Product Specifications
CAS Number
2050747-49-2
Product Name Alternative
ABCB1, Cluster of differentiation 243, CD243, Multidrug resistance protein 1, inhibit, Inhibitor, MDR1, P gp inhibitor 1, Pgp inhibitor 1, P-gp inhibitor 1, P-gp, Pgp, P-glycoprotein
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.16% (May vary between batches)
Solubility
DMSO:45 mg/mL (86.94 mM)
Smiles
COc1cc2CCN (CCc3ccc (Nc4nc (nc5ccccc45) -c4ccncc4) cc3) Cc2cc1OC
Molecular Formula
C32H31N5O2
Molecular Weight
517.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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