Oxidopamine hydrobromide
Oxidopamine hydrobromide (6-OHDA HBr) is a dopaminergic neurotoxin that induces inflammation via COX-2/PGE2 upregulation and IL-1β secretion. It is extensively utilized to create in vitro and in vivo Parkinson’s disease models for neurotoxicity and neuroinflammation research.
Product Specifications
CAS Number
636-00-0
Product Name Alternative
Prostaglandin E synthase, PGE synthase, PGE2, p-p38, p38 MAPK, SH-SY5Y cells, 6-Hydroxydopamine, 6-Hydroxydopamine hydrobromide, 6-Hydroxydopamine Hydrobromide, 6-OHDA, 6-OHDA Hydrobromide, 6-OHDA hydrobromide, Autophagy, attention-deficit hyperactivity disorder, Apoptosis, Caspase, COX, Dopamine Receptor, Dopamine, DopamineReceptor, Cyclooxygenase, inhibit, Mitophagy, Mitochondrial Autophagy, PC12 cells, Parkinson's disease, Oxidopamine, Oxidopamine hydrobromide, Oxidopamine Hydrobromide, neurotoxicity, neurotransmitter dopamine, Neuro-2a cells, Interleukin Related, Inhibitor, Lesch-Nyhan syndrome
Field of Research
Cell Biology, Neuroscience, Pharmacology & Drug Discovery
Purity
98.10% (May vary between batches)
Solubility
DMSO:125 mg/mL (499.82 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (15.99 mM) ; H2O:100 mg/mL (399.86 mM)
Smiles
Br.NCCc1cc (O) c (O) cc1O
Molecular Formula
C8H12BrNO3
Molecular Weight
250.09
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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