Paprotrain
Paprotrain is a potent and selective inhibitor of the mitotic kinesin MKLP-2, exhibiting an IC50 of 1.35 μM and a Ki of 3.36 μM against its ATPase activity. This small molecule is a valuable chemical probe for studying cytokinesis and cell division in both in vitro biochemical and cellular assays.
Product Specifications
CAS Number
57046-73-8
Product Name Alternative
Inhibitor, Paprotrain, MKLP-2, inhibit, Kinesin, (alphaZ) -alpha- (3-Pyridinylmethylene) -1H-indole-3-acetonitrile
Field of Research
Signal Transduction
Purity
99.69% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (16.31 mM) ; DMSO:125 mg/mL (509.62 mM)
Smiles
N#C\C (=C/c1cccnc1) c1c[nH]c2ccccc12
Molecular Formula
C16H11N3
Molecular Weight
245.28
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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