Peldesine

Peldesine (BCX-34) is a potent, orally bioavailable, and reversible inhibitor of purine nucleoside phosphorylase. It suppresses T-cell proliferation with an IC50 of 800 nM and has been investigated in preclinical research for cutaneous T-cell lymphoma, psoriasis, and HIV infection.

Product Specifications

CAS Number

133432-71-0

Product Name Alternative

DGuo, Analog, BCX 34, BCX34, BCX-34, inhibit, IL-2, immunosuppressive, Inhibitor, Nucleoside, Nucleoside Antimetabolite, Nucleoside Antimetabolite/Analog, NucleosideAntimetabolite, lymphoma, HIV, HIV Protease, HIVProtease, inosine, Human immunodeficiency virus, phosphorylase, PNP, Peldesine, T-cell, psoriasis, Purine nucleoside phosphorylase

Field of Research

Cell Biology, Infectious Disease & Virology, Molecular Biology, Protein Biochemistry

Purity

99.27% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (20.73 mM) ; DMSO:195 mg/mL (808.29 mM)

Smiles

C (C=1C2=C (NC1) C (=O) N=C (N) N2) C=3C=CC=NC3

Molecular Formula

C12H11N5O

Molecular Weight

241.25

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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