Pemigatinib
Pemigatinib is a potent and selective oral inhibitor of fibroblast growth factor receptors, with the highest activity against FGFR1-3. It is used in preclinical and clinical research for studying cancers driven by FGFR alterations, demonstrating efficacy in both cellular assays and animal models.
Product Specifications
CAS Number
1513857-77-6
Product Name Alternative
Cholangiocarcinoma, antineoplastic, FGFR4, FGFR3, FGFR2, FGFR1, Fibroblast growth factor receptor, FGFR, Inhibitor, inhibit, INCB054828, INCB-054828, INCB 054828, Orally, Pemigatinib
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.15% (May vary between batches)
Solubility
DMSO:26.58 mg/mL (54.52 mM) ;10% DMSO+90% Saline:0.1 mg/mL (0.21 mM)
Smiles
O=C (N1CC) N (C2=C (F) C=C (OC) C (OC) =C2F) CC3=C1C4=C (N=C3) NC (CN5CCOCC5) =C4
Molecular Formula
C24H27F2N5O4
Molecular Weight
487.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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