PDK4-IN-1 hydrochloride
PDK4-IN-1 hydrochloride is an orally bioavailable anthraquinone-based compound that potently inhibits pyruvate dehydrogenase kinase 4 (PDK4) with an IC50 of 84 nM. This inhibitor is a valuable research tool for studying metabolic disorders, such as diabetes and cancer, in both cellular and animal models.
Product Specifications
CAS Number
2310262-11-2
Product Name Alternative
Inhibit, p-Akt, PARP1, p53, metabolites, Inhibitor, caspase-3, Apoptosis, anticancer, anti-allergic, antidiabetic, BAX, BCL-xL, Pyruvate dehydrogenase kinase, PDK-4-IN-1 hydrochloride, PDK4-IN-1 Hydrochloride, PDK4, PDK4 IN 1 hydrochloride, PDK4IN1 hydrochloride, PDHK, PDHE1α, PDH kinase
Field of Research
Cell Biology, Metabolism Research, Signal Transduction
Purity
99.54% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.16 mM) ; DMSO:125 mg/mL (317.36 mM)
Smiles
Cl.O=C1c2ccccc2C (=O) c2c (cccc12) -c1cnn (c1) C1CCNCC1
Molecular Formula
C22H20ClN3O2
Molecular Weight
393.87
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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