BAY-1316957
Product Specifications
UNSPSC Description
BAY-1316957 is a potent, selective and orally active prostaglandin E2 receptor subtype 4 (EP4-R) antagonist with an IC50 of 15.3 nM for human EP4-R. BAY-1316957 has excellent agent metabolism and pharmacokinetics properties, and can be used for endometriosis research[1].
Target Antigen
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/BAY-1316957.html
Purity
99.73
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COCCN(C(C1=CC2=C(N(CC)C3=C2C=C(C)C=C3)C=C1)=N4)C5=C4C(C)=C(C(O)=O)C=C5
Molecular Weight
441.52
References & Citations
[1]Bäurle S, et al. Identification of a Benzimidazolecarboxylic Acid Derivative (BAY 1316957) as a Potent and Selective Human Prostaglandin E2 Receptor Subtype 4 (hEP4-R) Antagonist for the Treatment of Endometriosis. J Med Chem. 2019 Mar 14;62(5):2541-2563.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-111539/BAY-1316957-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-111539/BAY-1316957-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1613264-40-6
Available Sizes
Curated Selection
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