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Domperidone

Domperidone (R33812, Motilium) is a selective dopamine D2 and D3 receptor antagonist. Its primary action in the chemoreceptor trigger zone (area postrema) makes it a valuable research tool for studying the mechanisms and treatment of nausea and vomiting in both in vitro and in vivo models.

Product Specifications

CAS Number

57808-66-9

Product Name Alternative

D2, D3, Dopamine Receptor, DopamineReceptor, dopamine, Dopamine, Domperidone, blood-brain barrier, antiemetic, adverse, inhibit, oral, neurological, nausea, Inhibitor, vomit, R33812, R-33812, R 33812, symptoms, prokinetic

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

98.00% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.39 mM) ; DMSO:103 mg/mL (241.84 mM)

Smiles

ClC1=CC2=C (C=C1) N (C1CCN (CCCN3C (=O) NC4=CC=CC=C34) CC1) C (=O) N2

Molecular Formula

C22H24ClN5O2

Molecular Weight

425.91

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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